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doi: 10.1001/jama.2021.3224 [DOI] [PMC free article] [PubMed] [Google Scholar] 26

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No, it does not stimulate IGF-1 or muscle growth its effects are limited to fat metabolism pathways

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Proanthocyanidins also inhibit the enzyme cyclooxygenase (the same enzyme inhibited by aspirin and other non-steroidal medications)

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