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Even though tablets are also available, they are not that effective due to the benefits getting lost when the pills are digested

Of note, our recent findings also demonstrated that melatonin exerts antibacterial activity against GNB (e.g., Klebsiella , Pasteurella multocida and Pseudomonas aeruginosa ) through specifically inhibiting the activity of bacterial citrate synthase ( Figure 1E ), and the combination of colistin with melatonin enhances bacterial outer membrane permeability, oxidative damage and inhibits the effect of efflux pumps ( Figure 1F ) (126)

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AVD-deficient Wistar or Fischer rats also have impairments in hippocampal-dependent memory [142, 143]