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demonstrated the effectiveness of a depot system using HA-coated hybrid NPs composed of PLGA and cationic lipid dioleoyl trimethylammonium propane (DOTAP) incorporated into a thermosensitive hydrogel based on poloxamer 407 and HA 330 KDa (HA330)

doi: 10.1126/science.1109557 37 KoerberR

GSH is in a class of molecules called antioxidants, whose primary job is to alleviate oxidative stress

Although estrogen treatment has been shown to predispose ovariectomized rats to development of ulcerative colitis-induced tumor development [90], most studies to-date have shown that estrogen treatment decreases colonic paracellular permeability and reduces IBD symptom severity [89, 91, 92]