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The RVX therapy markedly decreased HIF-1 levels, with the 14 mg/kg dosage exhibiting the most substantial impact (71.8% reduction)

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2.3 The relationship between ferroptosis and other programmed cell death responses Ferroptosis is intricately linked to biological processes, including autophagy, endoplasmic reticulum stress, and inflammation, among others, and may be involved in the reciprocal regulation of recalcitrant diseases