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Current reviews comprehensively summarize these advances, analyzing IREs mechanisms, clinical outcomes, advantages, and limitations while highlighting critical research gaps and future directions for optimizing PEFs-based prostate cancer management ( 3.4 Melanoma PEFs represent a highly suitable therapeutic approach for melanoma, primarily because these tumors are typically located in superficial layers, allowing for direct percutaneous minimally invasive intervention that yields clinically significant outcomes

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These creams usually contain ingredients like hydroquinone, kojic acid, or vitamin C that help to inhibit the production of melanin in the skin