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Joshua Butcher at Oklahoma State University

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Unfortunately, this conventional clinical strategy sheds little light on the underlying infertility etiology or the functional integrity of a patients spermatozoa and has thus proven to be of limited utility in predicting fertilization success ( via the coupling of ultra-high magnification with machine learning [i.e., motile sperm organelle morphology examination (MSOME)], with the goal of standardizing the detection of morphological anomalies, it remains uncertain which elements of sperm structure define the functionality of this highly specialized cell

ProteinDNA conjugates were eluted from the bead complexes with elution buffer (100 mM NaHCO 3 and 1% SDS) for 30 min