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329 In conclusion, lung cancer is related to local microbiota dysbiosis, characterized by increased bacterial abundance, decreased -diversity, and altered bacterial composition

FIGURE 7 Melatonin and its Functions in Diabetic Neuropathy Melatonin is a broad-spectrum antioxidant with remarkable therapeutic effects against ROS-related diseases through the regulation of oxidative stress (X

However, higher dietary Se is reported to improve immunocompetence by modulating the synthesis of inflammatory mediators 8,10 , supporting T- and B-cell development 23 , and maintaining the Th1/Th2 balance

In accordance with these and other observations showing that fatty acids may induce ROS generation in diverse types of cells, 3234 we have extended these findings ascertaining that LA prompts ROS-mediated apoptosis also in breast and endometrial cancer cells through the subsequent activation of relevant transduction pathways