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Inflammatory responses associated with PD induce the activation of the Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-B) signaling pathway, which promotes the overexpression of -syn

This causal relationship is particularly critical in the pathogenesis of IBD, as excessive polarization and activation of M1 macrophages are key contributors to sustained intestinal inflammation and tissue damage

Studies by DSC have shown, that the temperatures of the pretransition and the main phase transition of SUVs of DPPC are 28.0 C and 37.2 C, respectively, whereas the corresponding temperatures for large unilamellar vesicles (LUVs) of DPPC are 33.8 C and 41.4 C, respectively 18

Makled et al