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10.1016/j.jff.2021.104716 J Funct Foods

doi:10.1016/j.foodchem.2020.127459 Sobral AF, Cunha A, Silva V, Gil-Martins E, Silva R, Barbosa DJ

STAT3 cooperates with phospholipid scramblase 2 to suppress type I interferon response

Generally, the tissue distribution and the persistence of expression of lipoplex and polyplex systems is mainly dependent, like with small molecular drugs following parenteral administration, also on the pharmacokinetics (clearance, distribution volume), the formulation (size, charge, PEGylation, etc.) and the dosage regimen (high volume bolus, sequential injection, constant infusion)