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The role of ferroptosis in blood-brain barrier injury

H., Inman, D

Methylation alterations in genes such as sirtuin1 (SIRT1), Ankyrin 1 (ANK1), Ribosomal protein L13 (RPL13), Rhomboids family member 2 gene (RHBDF2), and Cadherin 23 (CDH23) have also been implicated in AD pathogenesis, influencing A and tau pathways ( Table 2 )

Omaveloxolone, a synthetic oleanolic acid derivative, activates the Nrf2 pathway to protect cells from ferroptosis and shows potential in treating mitochondrial dysfunction-related conditions (Pilotto et al., 2024)