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One study suggested that hyperglycemia in patients with diabetes could affect thiamin re-uptake by decreasing the expression of thiamin transporters in the kidneys (42)

In addition, this period involves increased NADPH synthesis by redirecting glucose metabolism through the pentose phosphate pathway (PPP)

Results The PPP is dynamically regulated in the growth plate To study whether growth plate chondrocytes adjust their metabolic profile in relation to the various anabolic processes during the successive phases of differentiation, we performed scRNA-seq on isolated and digested growth plates from 3-day-old mice (Fig

Research indicates that GCG excess, rather than insulin deficiency, is crucial for diabetes pathogenesis