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Methylene blue, first line treatment in a clinical situation, has been demonstrated ineffective in reducing perfusion-associated methaemoglobinaemia and currently there is no established intervention to address this problem during NMP 11

Ge B, Song Y, Zhang Y, Liu X, Wen Y, Guo X

This matches the convenience profile of semaglutide and tirzepatide, which researchers already prefer for adherence reasons

This observation prompted us to run a competitive reaction in which a peptide thioester and an equimolar mixture of SetCys and Cys peptides were reacted in the presence of MPAA (Fig