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Specifically, the occurrence of peptide and protein aggregation in biological systems can cause diseases and in pharmaceutical drug products induce adverse immunological responses 10,11,12

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Results Oxidative stress in FH-deficient cells To elucidate the metabolic changes that occur on the loss of FH, we utilized the previously characterized mouse FH-deficient kidney cells ( Fh1 / ) and their wild-type (wt) isogenic control ( Fh1 fl/fl ) (ref

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