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Mobasheri, A

doi: 10.1016/j.biopha.2024.116727 77

Direct supplementation of cysteine can induce rapid elevations in highly cytotoxic hydrogen sulfide levels

While CAR-T therapy has demonstrated remarkable efficacy in hematologic malignancies such as multiple myeloma and relapsed/refractory B-cell lymphoproliferative disorders (leukemias, lymphomas) ( Figure 1 To overcome the antigen selection hurdle, significant research focuses on identifying neoantigens and unique splice variants arising from genomic alterations and aberrant RNA splicing in tumors