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Glutathione regulates the thiol redox state of the cells positively affecting NMDA receptor function and plasticity disrupted by PNEE in the dentate gyrus of adult males, and recovered by a diet enriched with n-3 from birth to adulthood (45) (Figure 1)

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After the signal is cleaved, the resulting unique precursor pro-GGT is modified through a self-proteolytic cleavage event termed autoprocessing, forming an active mature heterodimer of large and small subunits (Tate and Meister, 1981

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