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These gaps highlight the need for future research to move beyond descriptive associations toward systematic dissection of PKD mutationferroptosis crosstalk, cell type-specific functions, and clinical validation

Activated LINE elements generate abundant RNADNA hybrids, which are recognized as foreign nucleic acid signals by the cGAS-STING pathway, inducing immune responses and amplifying inflammatory signals closely linked to neuroinflammation in AD

The Anti-Inflammatory Power of Spices While the "heat" from chilies has a temporary effect, other spices often found in spicy cuisine may have more profound, long-term benefits for thyroid healthparticularly for those with autoimmune conditions like Hashimotos thyroiditis or Graves disease

Research involving BPC-157 remains ongoing, and long-term human safety data is limited