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Established measure groups and respective weightings were developed and maintained with interested parties, expert and public input upholding an Overall Hospital Quality Star Rating guiding principle of transparency

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It can, but the evidence is weaker than the label-dose weight-loss evidence

The authors reported that high intracellular levels of the lactone caused apoptotic cell death by upregulation of COX-2 mRNA and protein, as well as increased formation of peroxisome proliferator activated receptor (PPAR)-activating PGD2