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Their primary mode of action involves binding to ergosterol, a key sterol component of fungal cell membranes, leading to the formation of pores that disrupt membrane integrity and cause leakage of intracellular ions such as Na + , K + , H + , and Cl - , ultimately inhibiting fungal growth (Gray et al., 2012

Intense strength training followed by a sauna session is more draining on neuromuscular performance than aerobic endurance exercise followed by a sauna

As appetite suppression deepens, many patients reduce not just food intake but also fluid consumption, creating a state of mild dehydration that stresses the cardiovascular system