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It is unknown whether ROS exert their effects at the transcriptional levels by directly activating certain redox-sensitive transcriptional factors (TF) or, indirectly, by promoting the release of cytokines as part of the inflammatory response secondary to the oxidative tissue injury which may, in turn, activate a different set of TFs

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They restore microcirculation aiding in the delivery of nutrients and oxygen to the tissues, improve capillary resistance decreasing its permeability and help to restore lymphatic draining, facilitating the elimination of waste material and toxins and impeding fluid retention and oedema formation