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10.1523/jneurosci.3906-03.2004 110 SambandanS.SauerJ

3.1 Molecular mechanisms of mitochondrial biogenesis Mitochondrial biogenesis is a strictly regulated process

Therefore, impaired renal function would likely impact both plasma and urine PK of pudexacianinium: compared with those without renal impairment, theoretically plasma concentration would be higher, urinary excretion would be lower, and urine concentration would be lower in participants with renal impairment