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* Correspondence: Zhongquan Zhu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Briefly, the gene of the M pro was cloned into the PGEX-6p-1 vector, which has a Nsp4-Nsp5 and a PreScission cleavage site at the N- and C-termini, respectively, to generate the authentic target protein

0.25 mg = 10 clicks (approx.) 0.5 mg = 20 clicks (approx.) 1.0 mg = 40 clicks (approx.) 1.7 mg = 68 clicks (approx.) 2.4 mg = 96 clicks (approx.) Every pen model is slightly different when it comes to the number of clicks

Figure 2 Discussion A number of studies have suggested the important role oxidative stress plays in the pathophysiology of MS, and that markers of oxidative stress are increased in MS lesions ( To our knowledge, this is the first study evaluating a possible effect of NAC in patients with MS, and specifically using FDG PET to measure cerebral glucose metabolism