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Further, research into senolytic drugs is aims at developing formulations that ensure effective absorption & bioavailability when taken orally

Thomsen et al., 2017)

Therefore, oxidative stress can cause gastrointestinal symptoms such as diarrhea and constipation by exacerbating intestinal mucosal damage and disrupting the intestinal barrier

Elevated levels of calcium, sodium, and adenosine diphosphate in ischemic cells stimulate excessive production of mitochondrial oxygen radicals, causing damage to lipids, proteins, nucleic acids, and carbohydrates within the neurons [71]