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However, the precise pathophysiological mechanisms underlying VZV reactivation and its subsequent spread from the sensory ganglia and the dorsal horn of the spinal cord to the central nervous system remain incompletely understood

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Nat Immunol 5: 818827 Jones RG, Bui T, White C, Madesh M, Krawczyk CM, Lindsten T, Hawkins BJ, Kubek S, Frauwirth KA, Wang YL et al (2007) The proapoptotic factors Bax and Bak regulate T cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis