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Safety, tolerability, and biologic activity of AXA1125 and AXA1957 in subjects with nonalcoholic fatty liver disease

Despite their theoretical benefits, clinical outcomes in HF are mixed

Germande O, Ducret T, Quignard JF, Deweirdt J, Freund-Michel V, Errera MH, Cardouat G, Vacher P, Muller B, Berger P, Guibert C, Baudrimont M, Baudrimont I (2022) NiONP-induced oxidative stress and mitochondrial impairment in an in vitro pulmonary vascular cell model mimicking endothelial dysfunction

(4) The peptide was suggested to significantly lower ROS levels, unlike higher concentrations that did not demonstrate similar protective actions