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& Fujita, M

The importance of consistent dosing Synergy requires consistency

compositions of the invention comprise or used in combination with an effective amount of one or more other agents useful for prostate cancer therapy, including but not limited to: external-beam radiation therapy, interstitial implantation of radioisotopes (i.e., 125 I, palladium, iridium), leuprolide or other LHRH agonists, non-steroidal antiandrogens (flutamide, nilutamide, bicalutamide), steroidal antiandrogens (cyproterone acetate), the combination of leuprolide and flutamide, estrogens such as DES, chlorotrianisene, ethinyl estradiol, conjugated estrogens U.S.P., DES-diphosphate, radioisotopes, such as strontium-89, the combination of external-beam radiation therapy and strontium-89, second-line hormonal therapies such as aminog radioisotopes i.e., 125 I, palladium, iridium patients with pre-cancerous high-grade prostatic intraepithelial neoplasia are administered a composition of the invention to treat the disorder and decrease the likelihood that it will progress to malignant prostate cancer

After that, each reaction mixture (25 L) was loaded in 7.5% SDS along with protein marker, and electrophoresis was performed at 4 C