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There are a number of ways you can set yourself up for a sustained quit

4 The combined use of nicotine replacement, bupropion (Zyban), and social or behavioral support can increase the quit rate to 35 percent

Found on a corpse inside Cell 004 in the prisoner block, which can be accessed after completing the training sequence in the Training Room

There are prescription medications available to help reduce cravings or make using tobacco/nicotine less pleasurable, such as nicotine replacement patches/gum/sprays/inhalers/lozenges or medications that dont contain nicotine like varenicline/Chantix or bupropion/Wellbutrin