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Taken together, the present results support the idea that L-carnitine induces activation of the AKT pathway, and inhibits the TNF--induced increase in MAFbx expression by decreasing FOXO3a protein expression and promoting FOXO3a phosphorylation

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3,3-Dichlorobenzidine is another aromatic amine associated with bladder cancer, primarily used in pigment and dye production, and has been shown to increase DNA damage risk in bladder epithelial cells (Ghosal and Iba, 1990