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Oleinick NL, Xue LY, Friedman LR, Donahue LL, Biaglow JE

Homocysteine, through activation of NMDA receptors, induces Ca +2 , leading to excitotoxicity, astrocyte activation with release inflammatory mediators, and matrix metalloproteinase (MMP) activation with subsequent BBB injury and microvascular inflammation (Kamat et al

Recently, we demonstrated that metabolism of glutathione (GSH), a potent antioxidant that occurs abundantly in most cell types of many organisms, is inextricably linked to the processes that facilitate melanin formation

Some therapeutic strategies for neutrophils to control the exacerbation of inflammation include promotion of inflammation driven by neutrophils extracellular traps and inhibition of neutrophils reverse migration [105, 106]