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After 7d of selection, the cells were used in their respective assays

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Data from preclinical studies is promising but more human trials will need to be conducted to determine the full extent of KPV's abilities, as well as its safety and dosing parameters

In agreement with the decrease in TEER and increase in BBB paracellular permeability, tight junction proteins and adherens junction protein, -catenin, expression and localization are also altered with LPS treatment [71]