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Effect of glutathione depletion on Glutathione S-Transferase and Glutathione reductase activities In view of the major changes induced DEM but not BSO on cell proliferation we determine GST and GR activity in 3T3 fibroblasts (table 1 and table 2, respectively, supplementary data)

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Although the main focus of this review is T cells, experimental results obtained from other cell types, such as macrophages, also suggest that the serine-glutathione synthesis pathway plays a key role in regulating inflammatory responses