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While some studies pointed towards a general association of meat with NAFLD [73,120,121], more recent observational longitudinal studies [122-124] and cross-sectional studies [125,126] have linked high consumption of only red meat to an increased prevalence of NAFLD [95]

In mice, knockout of ChREBP has been shown to reduce hepatic fatty acid synthesis by 65% compared to wild-type controls, but also to promote insulin resistance, delayed glucose clearance, and severe intolerance to simple carbohydrates, such as sucrose and fructose (resulting in death in the majority of animals) due to an inability to shunt fructose into glycolytic pathways [48]

Dky tomu je pro lidsk enzymy prakticky nestraviteln vtina pejde trvicm traktem beze zmny