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Patients should talk to their oncologist about their own risks

Our large sample size enabled us to demonstrate a U-shaped relationship between folate and FPG levels and may explain the opposite associations reported in different populations

It should not be prescribed concurrently with monoamine oxidase inhibitors (MAOIs) or other medications that significantly alter serotonin pathways due to the risk of serotonin syndrome

According to clinical research parenteral administration (intramuscular or intravenous) is preferred over other drug administration routes in case of emergency situations as it provides first-pass metabolism avoidance, reliable therapeutic concentrations and better bioavailability of dosage (2) It can also be used in situations when oral route is not feasible