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7.3.3 Safety and specificity concerns Long-term safety assessment remains paramount, particularly regarding the theoretical risk of impairing tumor surveillance by chronically inhibiting a controlled cell death pathway, potential off-target effects of RNA-based therapies, and the challenge of achieving cell-type specificity without affecting essential ferroptosis functions in other tissues

We are now in a better position to design vaccines to induce immunity that can cross-recognize current variants and other human and animal coronaviruses

In addition, investigation of the mitochondrial function of 1919 PSPH amp and PSPH V116I GBM cells revealed an elevated proton leak in 1919 GBM PSPH V116I cells (Fig