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Furthermore, our previous omics analysis of fibroblasts isolated from a MSS patient identified an upregulation of CAT and both the isoforms of SOD (Cu-ZnSOD, MnSOD) 26,30

By enabling timely risk assessment, AI-driven predictive models can guide preventive strategies, minimizing the risk of complications and improving long-term patient outcomes

A post-hoc subgroup analysis of that trial suggested benefit of prasinezumab in subjects with faster progression [209] and a comparison of MDS-UPDRS progression during the 4-year open-label extension phase with historical controls showed divergent trajectories in favour of prasinezumab from year 2 of treatment onwards [210]

Huang and Pranata, 2020