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On the other hand, some studies suggest that polyphenols have effects on the expression of various inflammatory mediators, including interleukin-1beta, (IL-1), interleukin-6, (IL-6), and tumor necrotic factor alpha (TNF-) [27]

Notably, that CD40 ligand and IL-4 stimulation led to increase of mitochondrial sSOX in AZD-5991 combination with CB-839 compared to unstimulated cells