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This condition may cause chest pain, heart attack, heart failure, arrhythmias or death

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This premarket application deadline for currently marketed deemed products has shifted over the years from August 2018 to August 2022 to finally, after a court order, September 9, 2020.[13] This PMTA deadline applied to all ENDS products except for non-tobacco and non-menthol flavored cartridge-based ENDS (such as the JUUL), as well as any ENDS product that is targeted to minors or likely to promote ENDS use by minors, or for which the manufacturer has failed to take adequate measures to prevent minors access

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