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Controversies in Nephrology and Hypertension

Metformin influences progression in diabetic glioblastoma patients

For example, mitochondrial autophagy can maintain a healthy number of mitochondria, prevent damage caused by mitochondrial morphology destruction, reduced oxidative phosphorylation activity, mitochondrial membrane potential collapse, and ATP synthesis, enhance mitochondrial autophagy, inhibit mitochondrial metabolic processes, reduce GSH rapid consumption caused by Cys deprivation, lipid ROS generation, and ferroptosis (Gao et al., 2019