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Health Effects of Using Nicotine Some short- and long-term health effects of using nicotine include: Gum irritation and dry mouth Nausea or dizziness if you use very high doses Increased heart rate and blood pressure Risk of oral health issues with heavy, prolonged use Unlike cigarettes, nicotine pouches dont stain teeth and don't expose your lungs to carcinogens, but users should still practise good oral hygiene