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Cigarette smoke contains high concentrations of aldehydes, such as butyraldehyde, isobutyraldehyde, propionaldehyde, acetaldehyde, formaldehyde, acrolein, propanal, and MDA ( The major pathological implication of aldehyde exposure on the lungs includes oxidative stress, immune dysfunction, membrane disruption, histone modification, and mitochondrial dysfunction

31 Another study evaluated urinary delta-9 carboxy-THC concentrations in 14 individuals following a 4 week administration of a high CBD product