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These fibers were observed in histological samples from smokers with lung cancer.6 It is also known that fragments of cellulose acetate are separated from the filter of cigarettes when they are produced, as is the case with CAF, so they are defective, and should therefore be excluded from the production line, something that could also be detected by manufacturers and was known to them for more than 40 years, thus acting negligently.8 In the mid-1960s, the Surgeon General of the United States of America already considered cigarette filters useless to reduce harm to the smoker.9 In fact, epidemiological data collected between the 1970s and the early 2000s continued to support this conclusion: that the near-universal adoption of cigarette filters has done little to protect smokers.4 In 2011, a team of United States and Japan researchers stated that switching from unfiltered cigarettes to filter appears to have, like we have already said, simply altered the most common type of lung cancer, from squamous cell carcinoma to adenocarcinoma.10 Similarly, there is still no convincing evidence that cigarette filters have done anything to mitigate other risks to the smoker's health, such as heart and respiratory.9 A recent study11 indicate that filter ventilation alters tobacco combustion (with more smoke toxicants), get smoker to go deeper and inhale more smoke to maintain nicotine rate and causes a false perception of lower health risk
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Nicotine affects the autonomic nervous system and can lead to vomiting, hypersalivation, rapid heart rate, tremors, weakness, seizures, and respiratory failure
