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Im currently reading Joan Didions books, which are just beautiful and devastatingly honest

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Smoking a cigarette gives up to two milligrams of nicotine to the smoker

There were no correlations between galectin-8 and lung function and smoking history (Table 3), but it was observed that COPD patients who suffered from frequent acute exacerbations (2 or more/year) had significantly higher levels of galectin-8 in their serum (383.8 248.3 pg/ml) compared to healthy volunteers (209.1 120.8 pg/ml), and also when compared to COPD patients with infrequent exacerbations (176.2 100.0 pg/ml) (Fig