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Synthesis and in vitro evaluation of a peptidomimetic inhibitor targeting the Src homology 2 (SH2) domain of STAT6

Acutely, high intensity resistance exercise (80%100% 1RM) has been reported to increase carotid artery stiffness for up to 30 min post-exercise (Lefferts et al., 2014), MCAv for at least 1-min post exercise, and MCA pulsatility index in the immediate (30s) post-exercise period (Koch et al., 2005)