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Then, due to the proximity that macrophages and tumor cells reside in, interactions between VCAM-1 and the 4 integrins are promoted, which recruit Ezrin, a cytoplasmic adaptor protein that links the actin cytoskeleton to the cytoplasmic tail of VCAM-1, and ultimately results in tyrosine phosphorylation of Ezrin

In English, Lo recalls low, as in lo-fi, lo-res, lo-down, and so on Semblance Lacan defines the Semblance as an imaginary and symbolic construction that exists beyond anatomy, genetics, etc

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