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For a more accurate determination of participants exercise intensity in our study and the classification of exercise intensity into low, moderate or high, a maximal endurance test could have been conducted in advance (very time-consuming), or the exercise intensity could have been determined using a formula like in the studies of Conklin et al

The criteria set for the replication were (i) the same direction of effect as the discovery analysis and (ii) P 0.0045 in the replication studies (Bonferroni-adjusted for eleven SNVs at = 0.05)

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Although teen cigarette smoking is down in recent years, the use of e-cigarettes among young people has increased