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Because the statutory requirement to remove 340B units from rebate calculations does not begin until January 1, 2026, for the applicable year that begins on October 1, 2025, CMS proposes to apply the estimation percentage only to those units associated with claims with dates of service in the last three quarters of the applicable period (that is, January 1, 2026, through September 30, 2026)

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E-cigarettes are the most commonly used non-cigarette tobacco product among adults, and over 11 million US adults currently use e-cigarettes [25]

2. CDC