added chemicals in cigarettes and Tobacco: What's Burning? What Is In A Cigarette?

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This can result in increased peripheral resistance and elevated BP levels 22

But e-liquid allows gradually stepping down dose in a way not possible with tobacco

Smoking has an effect on most organs, here is how: Brain: Smoking increases the risk of having a stroke by at least 50% Heart: Smoking can double the risk of having a heart attack Bones: Smoking can cause bones to become week and brittle which increases the risk of osteoporosis in women Lungs: Smoking causes 84% of deaths from lung cancer and 83% of deaths from COPD Circulation: Smoking increases blood pressure and heart rate Fertility: Smoking can cause a lack of sexual appetite and impotency in men, and can make it harder for females to conceive Mouth and throat: Smoking can increase the risk of cancer in lips, tongue, throat, voice box and gullet Stomach: Smoking increases the chance of getting stomach cancer or ulcers Skin: Smoking prematurely ages skin by between 10 and 20 years The cost of smoking on your bank account On average, smokers smoke 20 cigarettes a day