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In general, exposure to pollutants induces pulmonary inflammation through the generation of oxidative stress 12,13 , defined as the imbalance in reactive oxygen species production, to the detriment of the antioxidant defence systems 14

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Hookah exposure induced a significant elevation of macrophages, lymphocytes, and neutrophils in broncho-alveolar lavage fluid and altered the levels of several cytokines

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