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In total, risk estimates from 19 studies were used for the meta-analysis where pooled RR estimate of second-hand smoking were calculated (Additional file 1: Table S3 and S4, Additional file 1: Figure S3S6) [3758]

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In the early stages of hypoxia, PAECs secrete increased levels of A20, which subsequently declined below normal levels in hypoxia-induced PH (HPH) rat models, suggesting that the NF-B signaling pathway is essential for the self-protection of PAECs (Li et al

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