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In the connective tissue deep to the ulcer there is increased vascularity and a mixed inflammatory infiltrate composed of lymphocytes, histiocytes and polymorphonuclear leukocytes

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But at the end of the third season, he receives a wound that cuts even deeper: His wife, Emma (Deanna Allison), leaves him because she can no longer bear to live with someone so blinded by his grief and driven by his work that her own needs are always an afterthought