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This time, its a stress-related hormone called corticotrophin-releasing hormone (CRH)

Birn hypothesized that trauma during an extraction or the presence of a bacterial infection somehow facilitates the release of plasminogen tissue activators in the post-extraction socket, resulting in the plasmin induction of fibrinolysis that dislodges the blood clot that formed after the extraction and causing a dry socket lesion6,9

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